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IJMS | Free Full-Text | Inhibitors of Chemoresistance Pathways in  Combination with Ara-C to Overcome Multidrug Resistance in AML. A Mini  Review
IJMS | Free Full-Text | Inhibitors of Chemoresistance Pathways in Combination with Ara-C to Overcome Multidrug Resistance in AML. A Mini Review

Radotinib enhances cytarabine (Ara-C)-induced acute myeloid leukemia cell  death | BMC Cancer | Full Text
Radotinib enhances cytarabine (Ara-C)-induced acute myeloid leukemia cell death | BMC Cancer | Full Text

How I treat older patients with acute myeloid leukemia
How I treat older patients with acute myeloid leukemia

Cytarabine Dose for Acute Myeloid Leukemia | NEJM
Cytarabine Dose for Acute Myeloid Leukemia | NEJM

Anti-leukemia effects of Ara-C@HFn and free Ara-C in AML mouse models.... |  Download Scientific Diagram
Anti-leukemia effects of Ara-C@HFn and free Ara-C in AML mouse models.... | Download Scientific Diagram

Cytarabine-resistant (320nM) acute myeloid leukemia (AML) MOLM-13 cell line
Cytarabine-resistant (320nM) acute myeloid leukemia (AML) MOLM-13 cell line

Pan‑RAF inhibitor LY3009120 is highly synergistic with low‑dose cytarabine,  but not azacitidine, in acute myeloid leukemia with <em>RAS</em> mutations
Pan‑RAF inhibitor LY3009120 is highly synergistic with low‑dose cytarabine, but not azacitidine, in acute myeloid leukemia with <em>RAS</em> mutations

The combination of CHK1 inhibitor with G-CSF overrides cytarabine  resistance in human acute myeloid leukemia | Nature Communications
The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia | Nature Communications

Targeting SAMHD1 with hydroxyurea in first‐line cytarabine‐based therapy of  newly diagnosed acute myeloid leukaemia: Results from the HEAT‐AML trial -  Jädersten - 2022 - Journal of Internal Medicine - Wiley Online Library
Targeting SAMHD1 with hydroxyurea in first‐line cytarabine‐based therapy of newly diagnosed acute myeloid leukaemia: Results from the HEAT‐AML trial - Jädersten - 2022 - Journal of Internal Medicine - Wiley Online Library

Ribonucleotide reductase inhibitors suppress SAMHD1 ara‐CTPase activity  enhancing cytarabine efficacy | EMBO Molecular Medicine
Ribonucleotide reductase inhibitors suppress SAMHD1 ara‐CTPase activity enhancing cytarabine efficacy | EMBO Molecular Medicine

Enhanced cytarabine-induced killing in OGG1-deficient acute myeloid leukemia  cells | PNAS
Enhanced cytarabine-induced killing in OGG1-deficient acute myeloid leukemia cells | PNAS

Cytarabine Dose for Acute Myeloid Leukemia | NEJM
Cytarabine Dose for Acute Myeloid Leukemia | NEJM

IJMS | Free Full-Text | Inhibition of Autophagy Does Not Re-Sensitize Acute  Myeloid Leukemia Cells Resistant to Cytarabine
IJMS | Free Full-Text | Inhibition of Autophagy Does Not Re-Sensitize Acute Myeloid Leukemia Cells Resistant to Cytarabine

RNA expression of genes involved in cytarabine metabolism and transport  predicts cytarabine response in acute myeloid leukemia | Pharmacogenomics
RNA expression of genes involved in cytarabine metabolism and transport predicts cytarabine response in acute myeloid leukemia | Pharmacogenomics

Cytarabine (cytosine arabinoside, Ara-C) chemotherapy drug molecule. Used  in treatment of acute myeloid leukemia (AML), acute lymphocytic leukemia  (AL Stock Vector Image & Art - Alamy
Cytarabine (cytosine arabinoside, Ara-C) chemotherapy drug molecule. Used in treatment of acute myeloid leukemia (AML), acute lymphocytic leukemia (AL Stock Vector Image & Art - Alamy

Induction therapy of AML with ara-C plus daunorubicin versus ara-C plus  gemtuzumab ozogamicin: a randomized phase II trial in elderly patients -  Annals of Oncology
Induction therapy of AML with ara-C plus daunorubicin versus ara-C plus gemtuzumab ozogamicin: a randomized phase II trial in elderly patients - Annals of Oncology

Cytarabine - Wikipedia
Cytarabine - Wikipedia

Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML |  Leukemia
Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML | Leukemia

Sequential Treatment with Cytarabine and Decitabine Has an Increased  Anti-Leukemia Effect Compared to Cytarabine Alone in Xenograft Models of  Childhood Acute Myeloid Leukemia | PLOS ONE
Sequential Treatment with Cytarabine and Decitabine Has an Increased Anti-Leukemia Effect Compared to Cytarabine Alone in Xenograft Models of Childhood Acute Myeloid Leukemia | PLOS ONE

Combination strategies to promote sensitivity to cytarabine-induced  replication stress in acute myeloid leukemia with and without DNMT3A  mutations - Experimental Hematology
Combination strategies to promote sensitivity to cytarabine-induced replication stress in acute myeloid leukemia with and without DNMT3A mutations - Experimental Hematology

Phase I and pharmacokinetic study of elacytarabine, a novel 5′-elaidic acid  derivative of cytarabine, in adults with refractory hematological  malignancies | Leukemia
Phase I and pharmacokinetic study of elacytarabine, a novel 5′-elaidic acid derivative of cytarabine, in adults with refractory hematological malignancies | Leukemia

A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of  leukemic cells in an acute myeloid leukemia mouse model - ScienceDirect
A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model - ScienceDirect

SNP analyses in cytarabine metabolizing enzymes in AML patients and their  impact on treatment response and patient survival: identification of CDA  SNP C-451T as an independent prognostic parameter for survival | Leukemia
SNP analyses in cytarabine metabolizing enzymes in AML patients and their impact on treatment response and patient survival: identification of CDA SNP C-451T as an independent prognostic parameter for survival | Leukemia

Ara-C metabolism. Ara-C: Cytarabine; Ara-CDP: Ara-C diphosphate;... |  Download Scientific Diagram
Ara-C metabolism. Ara-C: Cytarabine; Ara-CDP: Ara-C diphosphate;... | Download Scientific Diagram

Valproic acid enhances the antileukemic effect of cytarabine by triggering  cell apoptosis
Valproic acid enhances the antileukemic effect of cytarabine by triggering cell apoptosis

Acute myeloid leukaemia (AML) and cytarabine pharmacogenomics
Acute myeloid leukaemia (AML) and cytarabine pharmacogenomics

The effects of cytarabine combined with ginsenoside compound K  synergistically induce DNA damage in acute myeloid leukemia cells -  ScienceDirect
The effects of cytarabine combined with ginsenoside compound K synergistically induce DNA damage in acute myeloid leukemia cells - ScienceDirect

Cancers | Free Full-Text | Response and Toxicity to Cytarabine Therapy in  Leukemia and Lymphoma: From Dose Puzzle to Pharmacogenomic Biomarkers
Cancers | Free Full-Text | Response and Toxicity to Cytarabine Therapy in Leukemia and Lymphoma: From Dose Puzzle to Pharmacogenomic Biomarkers